Veterinary immunologist Dr. Nicola Mason joins Tripawd Talk to share exciting updates on a new clinical trial using CAR iNKT cell therapy to fight metastatic osteosarcoma in dogs. Learn how this breakthrough research is offering new hope for Tripawds and their families.
In this inspiring episode of Tripawd Talk, we’re joined by Dr. Nicola Mason, a leading veterinary immunologist at the University of Pennsylvania, to discuss her groundbreaking work in treating osteosarcoma in dogs.
Dr. Mason explains how immunotherapy — specifically CAR iNKT-cell therapy — is showing promise for dogs with metastatic bone cancer. You’ll learn about a brand-new clinical trial that may help dogs fight lung metastases after amputation and chemotherapy.
We also talk about the importance of immune system “fitness,” what researchers have learned from past clinical trials, and why the courage of pet parents participating in these studies is helping to advance care for both dogs and children with osteosarcoma.
Whether you’re facing a recent diagnosis or simply want to stay informed about the future of canine cancer care, this episode offers hope, insight, and valuable next steps.
Tripawd Talk #130: Hope for Osteosarcoma in Dogs with Dr. Nicola Mason
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About Dr. Nicola Mason
Dr. Nicola Mason, BVetMed, PhD, DACVIM, FRCVS, is a professor of Professor of Medicine and Pathobiology at the University of Pennsylvania School of Veterinary Medicine. She a leading researcher in the field of veterinary immunotherapy.
Dr. Mason has pioneered groundbreaking cancer treatments for dogs, including immunotherapies that activate the body’s own immune system to fight osteosarcoma.
Her current research focuses on innovative cellular therapies, including CAR iNKT cell treatments designed to target metastatic disease. Dr. Mason’s work is helping shape the future of cancer care for both pets and people.
Tripawd Talk Radio #130: Hope for Osteosarcoma in Dogs with Dr. Nicola Mason
Find resources mentioned during this episode below. See the related Tripawds News blog post (includes transcript).
RESOURCES
Mentioned in This Episode
New Clinical Trial at Penn Vet: Off-the-Shelf CAR T-Cell Therapy for Dogs with Osteosarcoma
https://tripawds.com/2025/07/17/penn-vet-clinical-trial-for-osteosarcoma-dogs/
Penn Vet Comparative Immunotherapy Program:
BAD LINK?
PBS Feature with Dr. Mason
Shelter Me: The Cancer Pioneers
https://www.pbs.org/video/the-cancer-pioneers-jemhoc/
AVMA Animal Health Studies Database:
https://ebusiness.avma.org/aahsd/study_search.aspx
Connect & Learn More
Facing osteosarcoma? You’re not alone. The Tripawds Support Circle is here for you:
https://tripawds.circle.so
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