Many Tripawd parents have mentioned neoplasene (also known as bloodroot) in our Tripawds Discussion Forums as a way to avoid conventional chemotherapy for certain types of dog cancer tumors, like mast cell cancer.
But up until our June 3 Tripawd Talk Radio show with Dr. Avenelle Turner, DVM, Diplomate ACVIM (Oncology), from the Veterinary Cancer Group in Southern California, we didn’t know much about this alternative treatment.
However, after Dr. Turner fielded a caller’s question about the efficacy of neoplasene during our show, she was kind enough to send us this downloadable white paper about neoplasene from the Journal of the American Veterinary Medical Association.
Why Vets Don’t Recommend Neoplasene
Neoplasene is known as an “escharotic” treatment that’s prepared with an herbal concoction containing bloodroot. This preparation is injected into the tumor site and is supposed to cause necropsy in subcutaneous tissues, which will supposedly cause subcutaneous tumors to die without any chemotherapy treatment.
Neoplasene was almost extinct after the 1970s invention of frozen tissue sectioning, but has recently been brought back into the spotlight as an alternative cancer therapy for humans and animals.
In this August 2011 paper, the JAVMA discusses the most important reasons to avoid neoplasene, such as:
- “Escharotics may be manufactured without regard to accepted standards and therefor may contain unknown quantities of pharmacologically active compounds or toxic adulterants.
- In the absence of biopsy prior to the escharotic administration, escharotic treatment precludes accurate histologic identification of tumor type.
- Escharotic treatment prevents accurate in vivo or histologic assessment of tumor margins. This is particularly important for invasive tumors of the skin and subcutis, such as mast cell tumors, soft tissue sarcomas and injection site sarcomas. Inadequate evaluation of tumor margins may result in cancer recurrence, possibly accompanied by more aggressive tumor behavior.
- Escharotic treatment is painful and cosmetically unappealing.
- Escharotic treatment has no documented history of success in human or veterinary medical literature.
- Escharotic administration may delay or prevent definitive treatment by a more effective means, notably surgical excision, which is curative for many cutaneous tumors.”
Read the frightening neoplasene case studies about two dogs who had horribly painful and costly reactions to neoplasene treatments by veterinarians, and you will probably want to do all you can to avoid this unproven, risky treatment for your dog’s cancer.
Download this white paper about neoplasene dangers today!